2017

An innovative chemical strategy for PCR-free genetic detection of pathogens by an integrated electrochemical biosensor.

The Analyst Petralia S, Sciuto EL, Di Pietro ML, Zimbone M, Grimaldi MG, Conoci S
阅读原文 PDF DOI PubMed

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示意图生成中

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中文摘要

英文摘要

An innovative chemical strategy integrated in a miniaturized electrochemical device was developed for sensitive detection of a pathogen genome (HBV virus) without any amplification step. The results show a limit of detection comparable to the standard qRT-PCR method (20 copies per reaction), paving the way to future development of genetic PoC devices addressing automatized and low-cost molecular diagnostics.

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