Size Controlled Copper (I) Oxide Nanoparticles Influence Sensitivity of Glucose Biosensor.

Copper (I) oxide (Cu₂O) is an appealing semiconducting oxide with potential applications in various fields ranging from photovoltaics to biosensing. The precise control of size and shape of Cu₂O nanostructures has been an area of intense research. Here, the electrodeposition of Cu₂O nanoparticles is presented with precise size variations by utilizing ethylenediamine (EDA) as a size controlling agent. The size of the Cu₂O nanoparticles was successfully varied between 54.09 nm to 966.97 nm by changing the concentration of EDA in the electrolytic bath during electrodeposition. The large surface area of the Cu₂O nanoparticles present an attractive platform for immobilizing glucose oxidase for glucose biosensing. The fabricated enzymatic biosensor exhibited a rapid response time of <2 s. The limit of detection was 0.1 μM and the sensitivity of the glucose biosensor was 1.54 mA/cm². mM. The Cu₂O nanoparticles were characterized by UV-Visible spectroscopy, scanning electron microscopy and X-ray diffraction.