2017

Developmental ERK Signaling Goes Digital.

Developmental cell Dessauges C, Pertz O
阅读原文 PDF DOI PubMed

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示意图生成中

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英文摘要

Reporting in Developmental Cell, de la Cova et al. (2017) present a biosensor to measure ERK activity dynamics in C. elegans larvae. They find that fate decision signaling involves frequency-modulated, digital ERK activity pulses. These findings may explain how graded morphogen signals are converted into precise and robust cell fate patterns.

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