A widened emission window of the peroxydisulfate-oxygen system for the detection of L-alanine.

Peroxydisulfate-oxygen (S2O82--O2) system has become one of the most used systems in electrogenerated chemiluminscence (ECL) field. Due to S2O82- can be used as Fenton Reagent, this work designed an ECL biosensor based on the S2O82--O2 system for the detection of L-alanine in a widened emission window and using hemin/G-quadruplex and platinum and palladium nanowires (Pt-Pd NWs) to in situ generate O2 to amplify the ECL intensity. The proposed ECL sensor showed an excellent analytical property for the detection of L-alanine in a linear range of 5.0 × 10-3 M to 1.0 × 10-8 M with the detection limit of 3.3 × 10-9 M (S/N = 3). This work with high selectivity, stability and reproducibility may open a new door to apply S2O82- in ECL field.