2019

Quartz crystal microbalance for telomerase sensing based on gold nanoparticle induced signal amplification.

Chemical communications (Cambridge, England) Yang H, Li Y, Wang D, Liu Y, Wei W, Zhang Y, Liu S, Li P
阅读原文 PDF DOI PubMed

组成图示

示意图生成中

传感器类型

检测对象

检测原理

检测灵敏度

效应效果

传感器的构成

中文摘要

英文摘要

A novel circulating-flow quartz crystal microbalance (QCM) biosensing method has been established to detect telomerase. Oligonucleotide-functionalized gold nanoparticles (GNPs-cDNA) have been used to amplify the frequency change, which enable this QCM to be a sensitive biosensor for telomerase activity detection. The detection limit was as low as 37 cells per mL. The assay platform exhibited excellent selectivity.

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