Label-Free Detection of Transferrin Receptor by a Designed Ligand-Protein Sensor.

Advanced detection of biomarkers in biofluids plays an important role in disease diagnosis and prognosis. Current techniques with pre-labelling suffer from high cost and complicated operation, etc. Herein, we designed a label-free electrochemical biosensor for rapid detection of transferrin receptor with desirable linear range, sensitivity, specificity, reproducibility, and stability for practical applications.