2018

Detecting live bacteria instantly utilizing AIE strategies.

Journal of materials chemistry. B Kong TT, Zhao Z, Li Y, Wu F, Jin T, Tang BZ
阅读原文 PDF DOI PubMed

组成图示

示意图生成中

传感器类型

检测对象

检测原理

检测灵敏度

效应效果

传感器的构成

中文摘要

英文摘要

A new class of biosensor molecules evoking fluorescent emission by rotation-restricted binding with bacteria was examined for its applicability in detecting live bacteria instantly. The fluorogens possessed multiple tetraphenylethene (TPE)-cored boronic acids to oligomerize through complexation with cis-diols on bacterial surfaces, resulting in aggregation-induced emission (AIE). The fluorogen having two boronic acid units discriminated between live and dead bacteria by showing AIE activity only with the latter. Live bacteria were instantly detected by consequent treatment with reagents of three and four di-boronates (which showed AIE activity with both live and dead bacteria). This phenomenon may lead to a practical method for live bacteria detection.

关键词