2013

A gold nanoparticle-enhanced fluorescence polarization biosensor for amplified detection of T4 polynucleotide kinase activity and inhibition.

Journal of materials chemistry. B Huang Y, Chen J, Shi M, Zhao S, Chen ZF, Liang H
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检测灵敏度

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传感器的构成

中文摘要

英文摘要

A novel fluorescence polarization (FP) nanosensor based on λ exonuclease cleavage reaction and FP enhancement effect of gold nanoparticles (AuNPs) has been developed for the detection of T4 polynucleotide kinase activity and inhibition. This FP sensor exhibits higher detection sensitivity over traditional fluorescence sensors by two orders of magnitude.

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