Validation of transdermal alcohol concentration data collected using wearable alcohol monitors: A systematic review and meta-analysis.

OBJECTIVE: To evaluate the diagnostic accuracy of transdermal alcohol content (TAC) data (i.e. index test) collected with wearable alcohol monitors for assessment of alcohol use or any other alcohol related outcome (e.g., excessive alcohol use) among adults 18 and older. METHODS: We will systematically search MEDLINE, EMBASE, PsycINFO, and the Social Sciences Citation Index (SSCI, Web of Science) for TAC validation studies. The reference standards for this systematic review study are alcohol use data collected through self-reports, breathalyzers, or blood samples. If enough studies are available to conduct a meta-analysis, we will use a hierarchical regression approach to pool the results and obtain summary point estimates.