2023

A high-performance electrochemical biosensor using an engineered urate oxidase.

Chemical communications (Cambridge, England) Wei Z, Knaus T, Liu Y, Zhai Z, Gargano AFG, Rothenberg G, Yan N, Mutti FG
阅读原文 PDF DOI PubMed

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英文摘要

We constructed a high-performance biosensor for detecting uric acid by immobilizing an engineered urate oxidase on gold nanoparticles deposited on a carbon-glass electrode. This biosensor showed a low limit-of-detection (9.16 nM), a high sensitivity (14 μA/μM), a wide range of linearity (50 nM-1 mM), and more than 28 days lifetime.

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