2013

Detection of single-nucleotide polymorphisms based on the formation of an electron-transfer impeding layer on an electrode surface.

Chemical communications (Cambridge, England) Gao Z, Shen W, Deng H, Ren Y
阅读原文 PDF DOI PubMed

组成图示

示意图生成中

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检测原理

检测灵敏度

效应效果

传感器的构成

中文摘要

英文摘要

An electrochemical biosensor utilizing the electron-transfer impeding (insulating) power of a conducting polymer for label-free genotyping single-nucleotide polymorphisms is proposed. Excellent selectivity and sensitivity are accomplished through the engagement of a nuclease clean-up step and a cumulative signal generation/amplification process, respectively.

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