Convenient and selective "off-on" detection nitric oxide in solution and thin film with quinoline based fluorescence sensor.

Quinoline based fluorescence sensor (1) was synthesized and characterized with mass spectra (MS), ((1))H nuclear magnetic resonance (((1))H NMR) spectrometer, elemental analyses, and infrared (IR) spectra. Following fluorescence experiments demonstrate 1 can coordinate with copper ions, and lead to fluorescence completely quenched. The 1-copper complex was used as a "turn-on" fluorescence biosensor to convenient and highly effective detect nitric oxide (NO) over other radicals in solution and PCL-based thin film. The finding would enable the quinoline based fluorescence probe to be an "off-on" convenient NO fluorescence probe.