Defining the ATPome reveals cross-optimization of metabolic pathways.
Disrupted energy metabolism drives cell dysfunction and disease, but approaches to increase or preserve ATP are lacking. To generate a comprehensive metabolic map of g...
Aerosol Jet Printing Enabled Dual-Function Electrochemical and Colorimetric Biosensor for SARS-CoV-2 Detection.
An aerosol jet printing enabled dual-function biosensor for the sensitive detection of pathogens using SARS-CoV-2 RNA as an example has been developed. A CRISPR-Cas13:...
Recent advances and challenges in plant viral diagnostics.
Accurate and timely diagnosis of plant viral infections plays a key role in effective disease control and maintaining agricultural productivity. Recent advances in the...
Impedimetric Single Carbon Fiber Electrode for Ultrasensitive Detection of
This study introduces a novel biosensing approach for the detection of pathogen DNA in breast milk utilizing single carbon fiber electrodes (SCFE) enhanced with MXene ...
Biosensors as transformative tools for multiplex detection of respiratory viral pathogens.
Respiratory viral infections remain a major global health challenge, highlighting the need for rapid, sensitive, and accessible diagnostic approaches. Conventional dia...
COVID-19 rhapsody: Rage towards advanced diagnostics and therapeutic strategy.
The deadly global outbreak of coronavirus disease-2019 (COVID-19) has forged an unrivaled threat to human civilization. Contemplating its profuse impact, initial risk ...
Topological barrier to Cas12a activation by circular DNA nanostructures facilitates autocatalysis and transforms DNA/RNA sensing.
Control of CRISPR/Cas12a trans-cleavage is crucial for biosensor development. Here, we show that small circular DNA nanostructures which partially match guide RNA sequ...
A critical review of conventional and emerging technologies for the detection of contaminants, allergens and adulterants in plant-based milk alternatives.
The increasing popularity of plant-based milk alternatives (PBMAs) necessitates effective safety and authentication measures to ensure food product integrity and maint...
From Biosensors to Robotics: Pioneering Advances in Breast Cancer Management.
Breast cancer stands as the most prevalent form of cancer amongst females, constituting more than one-third of all cancer cases affecting women. It causes aberrant cel...
Discrimination of single-point mutations in unamplified genomic DNA via Cas9 immobilized on a graphene field-effect transistor.
Simple and fast methods for the detection of target genes with single-nucleotide specificity could open up genetic research and diagnostics beyond laboratory settings....
Current Advances in Paper-Based Biosensor Technologies for Rapid COVID-19 Diagnosis.
The global coronavirus disease 2019 (COVID-19) pandemic has had significant economic and social impacts on billions of people worldwide since severe acute respiratory ...
Modular Fabrication of Microfluidic Graphene FET for Nucleic Acids Biosensing.
Graphene field-effect transistors (GFETs) are widely used in biosensing due to their excellent properties in biomolecular signal amplification, exhibiting great potent...
Repeat DNA methylation is modulated by adherens junction signaling.
Through its involvement in gene transcription and heterochromatin formation, DNA methylation regulates how cells interact with their environment. Nevertheless, the ext...
Imaging of mtHyPer7, a Ratiometric Biosensor for Mitochondrial Peroxide, in Living Yeast Cells.
Mitochondrial dysfunction, or functional alteration, is found in many diseases and conditions, including neurodegenerative and musculoskeletal disorders, cancer, and n...
Metabolic engineering of a novel strain of electrogenic bacterium Arcobacter butzleri to create a platform for single analyte detection using a microbial fuel cell.
Electrogenic bacteria metabolize organic substrates by transferring electrons to the external electrode, with subsequent electricity generation. In this proof-of-conce...
Bacteriophage-based biosensors technology: Materials, fabrications, efficiencies and shortcomings.
UNLABELLED: Ongoing research in biosensor technologies has led to advanced functional materials for healthcare diagnostics, and bacteriophages (phages), demonstrating ...
Biosensors in Microbial Ecology: Revolutionizing Food Safety and Quality.
Microorganisms play a crucial role in food processes, safety, and quality through their dynamic interactions with other organisms. In recent years, biosensors have bec...
Recombinase Polymerase Amplification-Based Biosensors for Rapid Zoonoses Screening.
Recent, outbreaks of new emergency zoonotic diseases have prompted an urgent need to develop fast, accurate, and portable screening assays for pathogen infections. Rec...
Human Body Performance with COVID-19 Affectation According to Virus Specification Based on Biosensor Techniques.
Life was once normal before the first announcement of COVID-19's first case in Wuhan, China, and what was slowly spreading became an overnight worldwide pandemic. Ever...
The Lumiptosome, an engineered luminescent form of the apoptosome can report cell death by using the same Apaf-1 dependent pathway.
Detection of the apoptosis signature becomes central in understanding cell death modes. We present here a whole-cell biosensor that detects Apaf-1 association and apop...