Modeling Human Muscular Dystrophies in Zebrafish: Mutant Lines, Transgenic Fluorescent Biosensors, and Phenotyping Assays.

International journal of molecular sciences 2023 Tesoriero C, Greco F, Cannone E, Ghirotto F 等 7 人

Muscular dystrophies (MDs) are a heterogeneous group of myopathies characterized by progressive muscle weakness leading to death from heart or respiratory failure. MDs...

The development of an ingestible biosensor for the characterization of gut metabolites related to major depressive disorder: hypothesis and theory.

Frontiers in systems biology 2023 Densil A, George ME, Mahdi H, Chami A 等 25 人

The diagnostic process for psychiatric conditions is guided by the Diagnostic and Statistical Manual of Mental Disorders (DSM) in North America. Revisions of the DSM o...

DRAM1 confers resistance to

Autophagy reports 2023 Masud S, Xie J, Grijmans BJM, van der Kooij S 等 7 人

DRAM1 is an infection inducible autophagy modulator, previously shown to promote autophagic and lysosomal defense responses against the intracellular pathogen Mycobact...

Analysis of protein secretion in Bacillus subtilis by combining a secretion stress biosensor strain with an in vivo split GFP assay.

Microbial cell factories 2023 Lenz P, Bakkes PJ, Müller C, Malek M 等 9 人

BACKGROUND: Bacillus subtilis is one of the workhorses in industrial biotechnology and well known for its secretion potential. Efficient secretion of recombinant prote...