共 25874 条结果
Nanoscale advances
2025
Huraiya MA, Ramaraj SG, Shahadat Hossain SM, Chakrabarti K 等 6 人
With advancements in photonic technologies, photonic crystal fibers (PCFs) have become crucial components in developing highly sensitive and efficient biosensors. This...
Angewandte Chemie (International ed. in English)
2025
Wang P, Wang X, Chandra S, Lielpetere A 等 7 人
We propose a hybrid electrocatalytic-bioelectrocatalytic reaction cascade integrated on a gas diffusion electrode for CO2 reduction under selective formation of methan...
ACS synthetic biology
2025
De Paepe B, De Mey M
Since the description of the lac operon in 1961 by Jacob and Monod, transcriptional regulation in prokaryotes has been studied extensively and has led to the developme...
Bioorganic chemistry
2025
Xu Z, Zhang X, Pal C, Rozners E 等 5 人
A modified enzyme fragment complementation assay has been designed and validated as a turn-on biosensor for nucleic acid detection in dilute aqueous solution. The assa...
Drug and alcohol dependence
2025
Fairbairn CE, Han J, Caumiant EP, Benjamin AS 等 5 人
BACKGROUND: Trace amounts of consumed alcohol are detectable within sweat and insensible perspiration. However, the relationship between ingested and transdermally emi...
Cell structure and function
2025
Weisheng Z, Nakayama J, Inomata Y, Higashiyama S 等 5 人
Extracellular signal-regulated kinase (ERK) regulates multiple cellular functions through distinct activation patterns. Genetically encoded fluorescent probes are inst...
ACS sensors
2025
Gouveia G, Saateh A, Swietlikowska A, Scarpellini C 等 18 人
Continuous monitoring of acute inflammation can become a very important next step for guiding therapeutic interventions in severely ill patients. This Perspective disc...
Angewandte Chemie (International ed. in English)
2025
Aggarwal T, Wang L, Gutierrez B, Guven H 等 7 人
Fluorescent light-up aptamer (FLAP) systems are promising (bio)sensing platforms that are genetically encodable. However, FLAP-mediated detection of each distinct targ...
Nanoscale advances
2025
Khaliq N, Ali G, Rasheed MA, Khan M 等 7 人
TiO2 nanotube flow-through membranes (TNTsM) were fabricated via anodization of Ti foil and explored as a biosensing platform for creatinine detection. The electrodes ...
British journal of pharmacology
2025
Zhu Z, Guan Q, Xu B, Bahriz S 等 12 人
BACKGROUND AND PURPOSE: Sarcoplasmic reticulum Ca2+-ATPase (SERCA2a) is impaired in heart failure. Phosphodiesterases (PDEs) are implicated in the modulation of local ...
Drug and alcohol review
2025
DiMartini A, Behari J, Punzi J, Dunn M 等 9 人
INTRODUCTION: We aimed to determine acceptability and feasibility of innovative wearable alcohol biosensor monitors (ABM) for patients with alcohol-related liver disea...
Nanoscale advances
2025
Lin X, Yang Y, Zhu W, He X 等 5 人
MicroRNAs (miRNAs) play crucial roles in the regulation of immune cell differentiation and the immune response during allergic rhinitis (AR). Studies have shown that m...
Talanta
2025
García-Fernández D, Gutiérrez-Gálvez L, López-Diego D, Luna M 等 9 人
In this study, we present a novel electrochemiluminescent DNA biosensor designed for detecting breast cancer type 1 (BRCA1) gene mutations. The biosensor integrates gr...
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
2025
Zheng Y, Sun J, Ma Y, Zhang H 等 13 人
High sensitivity and high quality-factor are crucial for achieving outstanding sensing performance in photonic biosensors. However, strong optical field confinement an...
Synthetic and systems biotechnology
2025
Blázquez AB, Jiménez de Oya N
Flaviviruses affect the lives of millions of people in endemic regions and also have the potential to impact non-endemic areas. Factors such as climate change, global ...
Synthetic and systems biotechnology
2025
Luo B, Wu S, Liu W, Zhang D 等 12 人
YpsR, a pivotal regulatory protein in the quorum-sensing (QS) of Yersinia pseudotuberculosis(Y. pstb), is essential for molecular signaling, yet its molecular mechanis...
Biosensors & bioelectronics
2025
Aslan M, Seymour E, Brickner H, Clark AE 等 11 人
Diagnostic approaches that combine the high sensitivity and specificity of laboratory-based digital detection with the ease of use and affordability of point-of-care (...
Biosensors & bioelectronics
2025
da Silva IS, Cardoso AR, Reimer L, König A 等 8 人
Aggregation of alpha-synuclein (aSyn) occurs in presynaptic neurons and constitutes a key factor for the progression of Parkinson's disease, emphasising the urgency of...
The Journal of cell biology
2025
Tsuji T, Hasegawa J, Sasaki T, Fujimoto T
Phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] is a phospholipid essential for plasma membrane functions, but its two-dimensional distribution is not clear. Her...
Future microbiology
2025
Sinha S, Bachan Upadhyay LS
At present, the prevalence of infectious diseases is rising annually, making it an important risk factor for human health that should not be neglected. Consequently, i...