A Modular Approach to Tuning Emissive
We have shown that palladium-catalyzed cascade processes provide modular access to rigid quinoline-containing tetracyclic amines. This modular approach enables fine-tu...
Insights into the regulatory mechanisms and application prospects of the transcription factor Cra.
Cra (catabolite repressor/activator) is a global transcription factor (TF) that plays a pleiotropic role in controlling the transcription of several genes involved in ...
RuC nanosheet as a promising biosensing material for detecting the aromatic amino acids: a DFT study.
Density functional theory (DFT) calculations were performed to examine the potential of the RuC nanosheet as a biosensor towards the aromatic amino acids (AAA; tryptop...
Nanohexagonal iron barium titanate nanoparticles surface-modified NiFe
A nanocomposite of iron barium titanate/NiFe2O4 (FBT/NF) was synthesized using sol-gel techniques to form organized hexagonal structures. The effects of NiFe2O4 nanost...
Enzyme-encapsulated metal-organic framework ZIF-8-mediated biosensor for ultrasensitive detection of urinary prostatic exosomal protein using a glucose meter.
A highly sensitive and efficient home-use method is impressive and promising in the self-monitoring of chronic prostatitis (CP). Herein, we developed a glucose oxidase...
Development of a graphene field effect transistor-based immersible biosensor for immunodetection of the birch pollen allergen Bet v 1 in air samples.
Pollen traps, the current gold standard to determine pollen load and thereby the allergy season, are not sufficient to determine the allergenic risk. Therefore, the es...
Diagnostic accuracy of the point-of-care standard G6PD test™ (SD Biosensor) for glucose-6-phosphate dehydrogenase deficiency: a systematic review and meta-analysis.
BACKGROUND: Glucose-6-Phosphate Dehydrogenase deficiency (G6PDd) is a common genetic enzymopathy that can induce haemolysis triggered by various factors, including som...
Design of an innovative aptasensor for the detection of chemotherapeutic drug Fludarabine phosphate.
Monitoring the concentration of Fludarabine phosphate, a standard chemotherapeutic drug widely used in cancer treatment, is vital for ensuring the drug's safety and ef...
Essential magnetosome proteins MamI and MamL from magnetotactic bacteria interact in mammalian cells.
To detect cellular activities deep within the body using magnetic resonance platforms, magnetosomes are the ideal model of genetically-encoded nanoparticles. These mem...
Impact of Wearable Technology on Heart Failure Management.
BACKGROUND: Heart failure (HF) is a chronic and progressive condition that its management presents significant challenges in both clinical settings and patient self-ca...
Dielectrophoretic capture and electrochemical enzyme-linked immunosorbent assay of single melanoma cells at an array of interlocked spiral bipolar electrodes.
Analysis of single cancer cells is critical to obtain accurate patient diagnosis and prognosis. In this work, we report the selective dielectrophoretic capture and ele...
SydR, a redox-sensing MarR-type regulator of
Rhizobia associate with legumes and induce the formation of nitrogen-fixing nodules. The regulation of bacterial redox state plays a major role in symbiosis, and react...
Sensitive and Cost-Effective Tools in the Detection of Ovarian Cancer Biomarkers.
Women diagnosed with late-stage ovarian cancer suffer a very high rate of mortality. Accordingly, it is imperative to detect and diagnose the disease as early as possi...
Real-time imaging of cGMP signaling shows pronounced differences between glomerular endothelial cells and podocytes.
Recent clinical trials of drugs enhancing cyclic guanosine monophosphate (cGMP) signaling for cardiovascular diseases have renewed interest in cGMP biology within the ...
Crystal structure of the HMGA AT-hook 1 domain bound to the minor groove of AT-rich DNA and inhibition by antikinetoplastid drugs.
High mobility group (HMG) proteins are intrinsically disordered nuclear non-histone chromosomal proteins that play an essential role in many biological processes by re...
Natural volatiles preventing mosquito biting: An integrated screening platform for accelerated discovery of ORco antagonists.
Insect olfactory receptors are heteromeric ligand-gated cation channels composed of an obligatory receptor subunit, ORco, and one of many variable subunits, ORx, in as...
Development of a two component system based biosensor with high sensitivity for the detection of copper ions.
Recent advancements in bacterial two-component systems (TCS) have spurred research into TCS-based biosensors, notably for their signal amplification and broad input re...
Semiconductive-like behaviour and negative differential effect observed in self-assembled riboflavin layer on gold electrodes.
Riboflavin or vitamin B2 plays significant roles in metabolic reactions and energy production, establishing it as an important research subject in biology and medicine...
Design of a PIT biosensor based on plasmonic-graphene-black phosphorous hybrid for hypercholesterolemia detection.
Cardiovascular diseases are the primary and fundamental reasons of people death around the world. Precise, fast responding, compact and integrable biosensors are consi...
Colorimetric aptasensing of microcystin-LR using DNA-conjugated polydiacetylene.
Polydiacetylene (PDA) holds promise as a versatile material for biosensing applications due to its unique optical properties and self-assembly capabilities. In this st...