Application of Antibody-Powered Triplex-DNA Nanomachine to Electrochemiluminescence Biosensor for the Detection of Anti-Digoxigenin with Improved Sensitivity Versus Cycling Strand Displacement Reaction.

准确、快速、定量检测抗体对疾病或毒素爆发的防控具有重要意义。本文首次将抗体驱动的三链DNA纳米机器引入新型三元电化学发光（ECL）体系，用于抗地高辛（anti-digoxigenin, anti-Dig）的灵敏检测。该纳米机器由S0-SH、S1-Dig、S2-Dig和货物DNA（cargo DNA）组成，并负载于Au@Fe3O4磁性...