Electrochemical sensing interfaces based on hierarchically architectured zwitterionic peptides for ultralow fouling detection of alpha fetoprotein in serum.
本文构建了一种基于层级结构两性离子肽的电化学传感平台,用于超低污染和高灵敏蛋白质定量。通过组合长链两性离子肽CPPPPEKEKEKEK(Pep4)与短链肽CPPPPEKEKEK(Pep3),形成层级抗污肽刷,表现出优异抗污性能,并可进一步修饰甲胎蛋白(AFP)适配体,实现AFP的高灵敏检测。该层级肽刷传感器在1.0 fg/mL至1....