2 条结果 关键词:伯氨喹 ×

Field evaluation of quantitative point of care diagnostics to measure glucose-6-phosphate dehydrogenase activity.

PloS one 2018 Alam MS, Kibria MG, Jahan N, Thriemer K 等 10 人

葡萄糖-6-磷酸脱氢酶(G6PD)缺乏是全球最常见的酶病,但缺乏可靠的床旁定量检测。本研究在孟加拉国招募已知G6PD状态的参与者,评估两种新型定量G6PD即时诊断:Biosensor(BS,AccessBio/CareStart)和STANDARD G6PD(SG,SDBiosensor),并以分光光度法为参考。共入组158人,15...

Low risk of recurrence following artesunate-Sulphadoxine-pyrimethamine plus primaquine for uncomplicated Plasmodium falciparum and Plasmodium vivax infections in the Republic of the Sudan.

Malaria journal 2018 Hamid MMA, Thriemer K, Elobied ME, Mahgoub NS 等 15 人

背景:苏丹非复杂性疟疾一线治疗为青蒿琥酯(12 mg/kg)联合磺胺多辛/乙胺嘧啶(25/1.25 mg/kg,AS/SP),间日疟另用14天伯氨喹(3.5 mg/kg,PQ)。本研究评估该方案疗效。方法:纳入>1岁、镜检确诊恶性疟和/或间日疟患者,均接受AS/SP;恶性疟随机分为无PQ(Pf-noPQ)或单次0.25 mg/kg ...