1 条结果 关键词:参数估计 ×

Impedimetric biosignal analysis and quantification in a real-time biosensor system.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 2010 Messing DS, Ghindilis A, Schwarzkopf K

本文描述了一种实时、无标记的电化学阻抗生物传感器系统,重点介绍利用阻抗响应信号模型对检测过程进行定量分析。该系统以互指电极为换能器,通过小幅度正弦电压激励,在靶标分子与固定化探针结合后,测量液-固界面阻抗随时间的变化。作者建立了基于表面化学的阻抗模型,将阻抗幅值表示为基线偏移、指数增长幅值和时间常数的组合,并采用非线性参数估计算法从...