Determination of binding capacity and adsorption enthalpy between Human Glutamate Receptor (GluR1) peptide fragments and kynurenic acid by surface plasmon resonance experiments. Part 2: Interaction of GluR1270-300 with KYNA.
本文报道了人谷氨酸受体(GluR1)第三个肽片段 GluR1270–300 与犬尿喹啉酸(KYNA)相互作用的表面等离子共振(SPR)研究。该 31 肽通过固相合成获得,并将第 270 位色氨酸突变为半胱氨酸,以便通过巯基与金表面形成 Au–S 共价键,固定在玻璃基底 50 nm 金薄膜 SPR 芯片上。原子力显微镜(AFM)证实肽...