Cytotoxic, genotoxic and antimicrobial activity of caffeic and rosmarinic acids and their lithium, sodium and potassium salts as potential anticancer compounds.

本研究以大肠杆菌K-12 recA:gfp工程菌作为微生物生物传感器，评价咖啡酸（CA）、迷迭香酸（RA）及其锂、钠、钾盐的细胞毒性、遗传毒性、抗氧化和抗菌活性。细胞毒性按600 nm光密度计算生长抑制率，并估算20%抑制剂量；遗传毒性以recA:gfp诱导的GFP荧光为基础，用SFI相对对照的倍数增加（FI）表示；抗氧化用DPPH...