A novel strategy for detection of small molecules based on aptamer/gold nanoparticles/graphitic carbon nitride nanosheets as fluorescent biosensor.

本文报道了一种用于人血浆中小分子检测的新型超灵敏无标记荧光纳米适配体传感器。该传感器以石墨相氮化碳纳米片(g-C3N4NS)为荧光探针，利用其与适配体/金纳米粒子(AuNPs)共轭物之间的荧光共振能量转移(FRET)效应实现荧光猝灭。加入地高辛(DGX)后，适配体与DGX特异性结合，并在盐存在下诱导AuNPs聚集，使g-C3N4NS...