Blood and Breath Alcohol Concentration from Transdermal Alcohol Biosensor Data: Estimation and Uncertainty Quantification via Forward and Inverse Filtering for a Covariate-Dependent, Physics-Informed, Hidden Markov Model.
透皮酒精生物传感器无需受试者主动配合即可提供近连续测量,有望补充呼气酒精仪和饮酒日记。为使透皮酒精浓度(TAC)能稳定转换为血液/呼气酒精浓度(BAC/BrAC),本文提出一种基于协变量依赖、物理信息隐藏马尔可夫模型(HMM)的 BrAC 估计与不确定性量化方法。该 HMM 作为全身酒精前向模型,将 BrAC 与 TAC 作为双发射...