2 条结果 关键词:细胞基生物传感器 ×

Development of a Cell-Based Biosensor for Residual Detergent Detection in Decellularized Scaffolds.

ACS synthetic biology 2021 Ghorbani F, Abdihaji M, Roudkenar MH, Ebrahimi A

体外器官工程利用脱细胞全器官支架与自体干细胞,是替代传统移植的潜在策略,但制备细胞相容支架仍是关键挑战,目前缺乏高精度、特异性的评估方法。细胞基生物传感器(CBB)能以高灵敏度、高特异性、低成本和无创方式检测分析物。本文基于 NF-κB 诱导型启动子开发了用于残留去污剂检测的 CBB。作者将含 NF-κB 结合序列的核心启动子与近端...

Cryopreservation of a cell-based biosensor chip modified with elastic polymer fibers enabling ready-to-use on-site applications.

Biosensors & bioelectronics 2021 Özsoylu D, Isık T, Demir MM, Schöning MJ 等 5 人

含活细胞的细胞基生物传感器芯片难以长期保存,尤其是贴壁哺乳动物细胞在传感器表面易受冷冻损伤。本文提出一种传感器上冷冻保存(on-sensor cryopreservation, OSC)策略,将贴壁细胞在光寻址电位传感器(light-addressable potentiometric sensor, LAPS)表面于−80 °C冷...