Signal amplification by a self-assembled biosensor system designed on the principle of dockerin-cohesin interactions in a cellulosome complex.

为构建具有信号放大功能的自组装生物传感器，本研究利用厌氧梭菌细胞酶复合体中I型和II型dockerin–cohesin相互作用的不同特异性，设计并组装了一种蛋白模块型荧光传感系统。自组装单元（SA unit）由C. cellulovorans的I型cohesin模块、C. thermocellum的II型dockerin模块和两个I...