Effect of Sub-Minimum Inhibitory Concentrations of Tyrosol and EDTA on Quorum Sensing and Virulence of

Infection and drug resistance 2020 Abdel-Rhman SH, Rizk DE, Abdelmegeed ES

铜绿假单胞菌是多重耐药机会致病菌，群体感应（QS）调控其毒力因子表达。本研究评价酪醇（tyrosol）和乙二胺四乙酸（EDTA）亚最低抑菌浓度（sub-MIC）对铜绿假单胞菌PAO1的抗QS和抗毒力作用。采用紫色杆菌CV12,472生物传感器生物测定法检测抗QS活性，Miller法通过β-乳酰酶活性测定C4-HSL和C12-HSL，...

综述或非传感器论文 群体感应铜绿假单胞菌酪醇EDTA

Construction of a sensitive and specific lead biosensor using a genetically engineered bacterial system with a luciferase gene reporter controlled by pbr and cadA promoters.

Biomedical engineering online 2020 Nourmohammadi E, Hosseinkhani S, Nedaeinia R, Khoshdel-Sarkarizi H 等 13 人

细菌生物传感器是指经遗传工程改造、在环境物理或化学刺激下产生可测量信号的细菌体系。本研究设计并评价了两种以荧光素酶报告基因（luc+）为输出元件的细菌生物传感器：pGL3-luc/pbr和pGL3-luc/cad。前者将来自铜矿杆菌Cupriavidus metallidurans CH34质粒pMOL30的pbr启动子与pbrR调...

全细胞生物传感器 铅离子细菌生物传感器荧光素酶报告基因pbr启动子