A simple and efficient strategy for trace detection of ferroptosis-related miRNAs based on novel hydrophobic paper-based plasmonic substrate and "inverse molecular sentinel (iMS)" nanoprobes.

监测铁死亡相关微小RNA对脑出血患者的治疗和预后具有重要意义。本研究通过滴涂尺寸和形貌分布窄的哑铃状金纳米棒（DS Au nanorods）于疏水滤纸（h-paper）上，制备新型疏水纸基等离子体SERS基底；拉曼报告分子吸附于阵列表面，随机点SERS谱显示均匀且显著增强。将标记拉曼报告分子并与占位DNA杂交的发夹DNA修饰于SER...