Screening for cerebral amyloid angiopathy based on serological biomarkers analysis using a dielectrophoretic force-driven biosensor platform.
本研究利用高灵敏介电电泳(DEP)驱动生物传感器平台分析血浆淀粉样蛋白β(Aβ)1–40和Aβ1–42,评估根据Aβ-PET阳性及脑淀粉样血管病(CAA)神经影像标准分类受试者中精确筛查CAA的可行性。前瞻性纳入25例非阿尔茨海默病(non-AD)和19例阿尔茨海默病(AD)受试者,并按改良Boston标准分为CAA−与CAA+(可...