Polypyrrole/carbon dot nanocomposite as an electrochemical biosensor for liquid biopsy analysis of tryptophan in the human serum of normal and breast cancer women.

液体活检分析在缺乏肿瘤组织或患者状况不佳时具有重要价值。氨基酸代谢变化可辅助癌症诊断，色氨酸（Trp）的分解代谢监测有助于追踪癌症进展。本研究在铅笔石墨电极（PGE）表面构建过氧化聚吡咯/纳米碳点（Ov-Ox PPy/CDs）纳米复合修饰电极，用于人血清中Trp的灵敏检测。方波伏安法（SWV）下，Ov-Ox PPy/CDs/PGE对...