Novel fluorescein polymer-based nanoparticles: facile and controllable one-pot synthesis, assembly, and immobilization of biomolecules for application in a highly sensitive biosensor.

生物芯片与生物传感器制备的关键在于优化兼具高灵敏度与高特异性的光学或电化学检测技术。荧光聚合物纳米颗粒等光学方法因优势显著而推动诊断领域发展。本文报道了一种简便方法，开发新型荧光素聚合物纳米颗粒（FPNPs）并固定特定生物分子，用于高灵敏光学生物传感器。通过自由基聚合合成三种两亲性荧光素聚合物poly(FMA-r-NAS-r-MA)...