Immunoproteasome in the blood plasma of children with acute appendicitis, and its correlation with proteasome and UCHL1 measured by SPR imaging biosensors.
本研究旨在利用表面等离子共振成像(SPRI)生物传感器测定儿童急性阑尾炎患者血浆中免疫蛋白酶体浓度,并分析其与循环20S蛋白酶体及泛素羧基端水解酶L1(UCHL1)的相关性。研究纳入27名急性阑尾炎患儿(2岁9个月至14岁,平均9.5±1岁)和18名年龄匹配的健康对照,分别于术前、术后24 h和72 h采集静脉血并制备血浆。结果显示...