2 条结果 关键词:血小板来源微颗粒 ×

Identification and ultrasensitive photoelectrochemical detection of LncNR_040117: a biomarker of recurrent miscarriage and antiphospholipid antibody syndrome in platelet-derived microparticles.

Journal of nanobiotechnology 2022 Sun Z, Zhou Q, Yang Y, Li L 等 9 人

血小板来源微颗粒(PMPs)中长非编码RNA(LncRNAs)异常表达与免疫紊乱密切相关,可能导致抗磷脂抗体综合征(APS)和复发性流产(RM)。为探究PMPs中LncRNAs与RM/APS的关联,分析了RM/APS患者与健康对照者LncRNAs表达差异。芯片分析和RT-qPCR证实RM/APS患者LncNR_040117高表达。慢...

Graphene oxide-based biosensor for detection of platelet-derived microparticles: A potential tool for thrombus risk identification.

Biosensors & bioelectronics 2015 Kailashiya J, Singh N, Singh SK, Agrawal V 等 5 人

本文报道了一种基于氧化石墨烯(GO)的电化学生物传感器,用于检测血小板来源微颗粒(PMPs)。PMPs是动脉促血栓性疾病如急性心肌梗死(AMI)和中风的重要风险因素。传感器以玻碳电极为基底,表面固定GO层,并通过EDC/NHS活化羧基共价固定PAC1抗体;该抗体特异性识别PMP表面活性构象的整合素αIIbβ3。检测采用无标记电化学阻...