A novel electrochemiluminescent reagent of cyclometalated iridium complex-based DNA biosensor and its application in cancer cell detection.
本文报道了一种新型环金属化铱配合物[(ppy)2Ir(dcbpy)]+PF6-作为电化学发光(ECL)标记试剂,并用于构建高灵敏度DNA生物传感器及癌细胞检测。该铱配合物具有较高ECL效率,结合金纳米颗粒(AuNPs)信号放大和半胱胺生物条形码,可显著增强ECL信号。在DNA检测中,巯基化捕获DNA自组装于金电极表面,与目标DNA杂...