Facile Synthesis of pH-sensitive Germanium Nanocrystals with High Quantum Yield for Intracellular Acidic Compartment Imaging.
本文报道了一种绿光发射锗纳米晶(Ge nanocrystals, Ge NCs)生物传感器,用于监测细胞内溶酶体 pH 变化。该 Ge NCs 通过简便水相溶液法合成,避免了有毒或环境不友好试剂,光致发光量子产率显著提高至约 26%。其光致发光强度对 pH 5–6 区间的变化尤为敏感。与培养细胞共孵育时,纳米晶被细胞内化,并沿溶酶体...