Ultrasensitive electrochemical genosensor for direct detection of specific RNA sequences derived from avian influenza viruses present in biological samples.

本文报道了一种基于环氧菲啰啉–Fe(III)–氨基单链DNA（NH2-ssDNA）氧化还原活性层的电化学基因传感器，用于检测禽流感病毒来源的RNA。传感器制备包括：(I) 用氨基乙硫醇（AET）修饰金电极；(II) 通过点击化学将5,6-环氧-5,6-二氢-[1,10]-菲啰啉（Epoxy-Phen）接枝到AET自组装单分子层上；(...