Involvement of organic acids and amino acids in ameliorating Ni(II) toxicity induced cell cycle dysregulation in Caulobacter crescentus: a metabolomics analysis.

镍（Ni(II)）毒性可被多种细菌应对，但细菌对镍胁迫的响应机制仍不清楚。本研究考察 Ni(II) 毒性对 α-变形菌弯曲柄杆菌（Caulobacter crescentus）细胞增殖的影响，并揭示其在镍胁迫下存活的机制。结果显示，不同浓度 Ni(II) 显著影响弯曲柄杆菌生长：0.003 mM 仅轻微影响生长，0.008 mM 使...