High throughput surface plasmon resonance imaging method for clinical detection of presence and strength of binding of IgM, IgG and IgA antibodies against SARS-CoV-2 during CoViD-19 infection.
本文报道了一种高通量表面等离子共振成像(SPRi)方法,用于检测 CoViD-19 患者及非感染对照血清中针对 SARS-CoV-2 受体结合域(RBD)的 IgG、IgM 和 IgA 抗体。该方法在单次运行中同时测定最多 384 份患者样本的抗体同种型水平及其与 RBD 的结合强度。研究共纳入 102 例 CoViD-19 和非 ...