A biosensor based on a 3D-DNA walking machine network and distance-controlled electrochemiluminescence energy transfer for ultrasensitive detection of tenascin C and lead ions.

本文提出一种基于距离控制能量转移和三维DNA行走机器网络的电化学发光生物传感器，用于超灵敏、可控地检测不同类型靶标。该传感器以AuNPs@Fe3O4为纳米载体，负载CdS:Mn量子点修饰的发夹DNA S1、抗体标记DNA W1和DNA连接链H1/H2，形成三维DNA行走机器；通过两条DNA连接链杂交构建网络，提高装载量与质量传输。初...