2 条结果 关键词:BIRDS ×

Distribution of temperature changes and neurovascular coupling in rat brain following 3,4-methylenedioxymethamphetamine (MDMA, "ecstasy") exposure.

NMR in biomedicine 2015 Coman D, Sanganahalli BG, Jiang L, Hyder F 等 5 人

MDMA(‘摇头丸’)是一种滥用精神兴奋剂,可产生强单胺能刺激和全身高热。其产热涉及解偶联蛋白(UCP)激活,主要是骨骼肌 UCP-3,脑内缺乏 UCP-3,但其他 UCP 在丘脑等脑区表达,可能参与产热。本研究采用新型磁共振方法 BIRDS,结合外源温度敏感探针 TmDOTMA4-(铥离子与 DOTMA4- 大环螯合物),测量系统...

Lanthanide ion (III) complexes of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraaminophosphonate for dual biosensing of pH with chemical exchange saturation transfer (CEST) and biosensor imaging of redundant deviation in shifts (BIRDS).

Contrast media & molecular imaging 2015 Huang Y, Coman D, Ali MM, Hyder F

基于弛豫性的钆(Gd3+)磷酸盐配合物磁共振pH成像具有应用前景,但磁共振生物传感器成像也可通过检测镧系配合物本身的可交换或非交换质子实现。非交换质子(如–CHx)可用三维化学位移成像方法BIRDS检测,可交换质子(如–OH或–NHy)可用化学交换饱和转移(CEST)对比检测。本文测试了1,4,7,10-四氮杂环十二烷-1,4,7,...