Fabrication of an electrochemical biosensor composed of multi-functional Ag ion intercalated DNA four-way junctions/rhodium nanoplate heterolayer on a micro-gap for C-reactive protein detection in human serum.
炎症参与急性冠脉综合征的发病机制,C反应蛋白(CRP)可作为生物标志物。为精确检测CRP,作者构建了由八银离子嵌入多功能DNA四路连接体(MF-DNA-4WJ)和多孔铑纳米颗粒(pRhNP)异质层组成的微间隙电极CRP电化学生物传感器。通过C–C错配引入8个Ag+以提高导电性;每条DNA四路连接体包含CRP适配体序列、巯基锚定区及末...