1 条结果 关键词:DNA损伤应答 ×

Radiation-Responsive Promoters: Molecular Mechanisms, Screening Strategies, and Translational Applications as Radiation Biomarkers.

Current issues in molecular biology 2026 Xu N, Huang X, Zhou P

辐射响应启动子是一类功能独特的转录调控元件,可将辐射诱导的遗传毒性应激信号转化为可定量的基因表达输出。它们不直接测量分子损伤产物,而是通过协调的基因调控网络报告细胞对辐射应激的解读,在辐射生物标志物体系中占据独特机制位置。本综述系统分析五类主要辐射响应启动子:microRNA(miRNA)启动子、tRNA来源小RNA(tsRNA)启...