Label-free quartz crystal microbalance with dissipation monitoring of resveratrol effect on mechanical changes and folate receptor expression levels of living MCF-7 cells: a model for screening of drugs.
本研究采用带耗散监测的石英晶体微天平(QCM-D)对活 MCF-7 乳腺癌细胞进行实时、无标记监测,以评估白藜芦醇的抗肿瘤活性。作者分别构建聚-L-赖氨酸(PLL)修饰的 QCM-D 传感器和壳聚糖-叶酸(CS-FA)复合膜功能化金基底传感器:前者用于追踪白藜芦醇处理后细胞黏弹性、刚度等机械性能变化,后者用于监测细胞表面叶酸受体(F...