An amplified label-free electrochemical aptasensor of γ-interferon based on target-induced DNA strand transform of hairpin-to-linear conformation enabling simultaneous capture of redox probe and target.

本文报道了一种新型信号放大无标记电化学适配体传感器，用于高效检测γ-干扰素（IFN-γ）。该传感器基于目标诱导DNA发夹构象向线性构象转变，并实现氧化还原探针与目标的同时捕获。首先将金纳米颗粒（AuNPs）电沉积在聚酰胺胺树状分子（PAMAM）基质中，再滴加到二硫化钼（MoS2）纳米片上制备AuNPs-PAMAM/MoS2复合材料；...