Electrochemiluminescence biosensor for thrombin detection based on metal organic framework with electrochemiluminescence indicator embedded in the framework.

将三(4,4'-二羧酸-2,2'-联吡啶)钌(II)（Ru(dcbpy)3^2+）通过酰胺键与聚乙烯亚胺-L-赖氨酸（PEI-L-lys）连接，并负载于金属有机框架ZIF-8中，构建新型电化学发光（ECL）指示剂Ru-PEI-L-lys-ZIF-8。其中PEI-L-lys同时作为共反应物，无需额外加入共反应物。将铂纳米粒子（PtNP...