A Gold Nanoparticle-based Aptasensor for Specific Detection of CA125.
BACKGROUND: In this work, an aptamer-based biosensor was successfully developed based on the salt-induced gold nanoparticle (AuNP) aggregation phenomenon for the detec...
Current smartphone-assisted point-of-care cancer detection: Towards supporting personalized cancer monitoring.
With the rising incidence of cancer-related mortality, new enabling technologies are necessary to offer comprehensive molecular profiles of patients in order to assist...
Repression of microbial arsenite uptake and methylation by dissolved organic carbon.
Arsenic methylation is the microbe-mediated transformation of inorganic As into methylated species, an important component of the biogeochemical arsenic cycle in rice ...
Colorimetric nano-biosensor for low-resource settings: insulin as a model biomarker.
Biomarkers provide critical molecular insights into diseases and abnormal conditions. However, detecting them at ultra-low concentrations is a challenge, particularly ...
Intein-mediated thyroid hormone biosensors: towards controlled delivery of hormone therapy.
Although blood sampling and medical imaging are well-established techniques in clinical diagnostics, they often require long post-processing procedures. Fast and simpl...
An Advanced Healthcare Sensing Platform for Direct Detection of Viral Proteins in Seconds at Femtomolar Concentrations via Aerosol Jet 3D-Printed Nano and Biomaterials.
Sensing of viral antigens has become a critical tool in combating infectious diseases. Current sensing techniques have a tradeoff between sensitivity and time of detec...
Unlocking the potential of circulating small extracellular vesicles in neurodegenerative disease through targeted biomarkers and advancements in biosensing.
Neurodegenerative diseases (NDDs) gradually affect neurons impacting both their function and structure, and they afflict millions worldwide. Detecting these conditions...
Impaired autophagy flux contributes to enhanced ischemia reperfusion injury in the diabetic heart.
Myocardial ischemia/reperfusion (I/R) injury is exacerbated in diabetic individuals and animal models. We tested whether autophagy is an important cellular determinant...
Rapid, Multispecies Detection of SARS-CoV-2 Antibodies via a Meta-Surface Plasmon Resonance Biosensor.
Public health concerns have been raised by numerous reports of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) and its variations infecting a range o...
Assessing a Novel Thyroid-Stimulating Antibody Bioassay as a Predictor of Radioactive Iodine Therapy Efficacy in Graves' Disease.
OBJECTIVE: No studies have reported the use of the Biosensor TSAb assay (TSAb (Bio)) for predicting the therapeutic efficacy of radioactive iodine therapy (RAIT) for G...
Probing and imaging phospholipid dynamics in live cells.
Distinct phospholipid species display specific distribution patterns across cellular membranes, which are important for their structural and signaling roles and for pr...
Productive biosensing techniques empowered by all-dielectric metasurfaces.
Artificially designed, functional nanostructured surfaces, called metasurfaces, are an emerging platform for biosensing. Two major types of metasurface biosensors have...
A bibliometric and visualization analysis of electrochemical biosensors for early diagnosis of eye diseases.
Electrochemical biosensors can provide an economical, accurate and rapid method for early screening of disease biomarkers in clinical medicine due to their high sensit...
A genetically encoded fluorescent biosensor for sensitive detection of cellular c-di-GMP levels in
Cyclic di-guanosine monophosphate (c-di-GMP) acts as a second messenger regulating bacterial behaviors including cell cycling, biofilm formation, adhesion, and virulen...
From isolation to detection, advancing insights into endothelial matrix-bound vesicles.
Matrix-bound vesicles (MBVs), an integral part of the extracellular matrix (ECM), are emerging as pivotal factors in ECM-driven molecular signaling. This study is the ...
A Rewired NADPH-Dependent Redox Shuttle for Testing Peroxisomal Compartmentalization of Synthetic Metabolic Pathways in
The introduction of heterologous pathways into microbial cell compartments offers several potential advantages, including increasing enzyme concentrations and reducing...
Low-Cost and Portable Biosensor Based on Monitoring Impedance Changes in Aptamer-Functionalized Nanoporous Anodized Aluminum Oxide Membrane.
We report a low-cost, portable biosensor composed of an aptamer-functionalized nanoporous anodic aluminum oxide (NAAO) membrane and a commercial microcontroller chip-b...
A Microfluidic Biosensor for Quantitative Detection of
Microbial contamination is an important factor threatening the safety of Chinese medicine preparations, and microfluidic detection methods have demonstrated excellent ...
Synergistic Approach of High-Precision 3D Printing and Low Cell Adhesion for Enhanced Self-Assembled Spheroid Formation.
Spheroids, as three-dimensional (3D) cell aggregates, can be prepared using various methods, including hanging drops, microwells, microfluidics, magnetic manipulation,...
Recent Advances in Biosensors Using Enzyme-Stabilized Gold Nanoclusters.
Recently, gold nanoclusters (AuNCs) have been widely used in biological applications due to their ultrasmall size, ranging within a few nanometers; large specific surf...