Graphene nanoribbons: A state-of-the-art in health care.
Graphene nanoribbons are thin strips of single sheet graphene used in diagnoses and treatments of cancer, inflammation and Alzheimer's disease and considered as a good...
Simple paper-based colorimetric and fluorescent glucose sensor using N-doped carbon dots and metal oxide hybrid structures.
A new strategy for the fluorescent and colorimetric sensing of hydrogen peroxide (H2O2) and glucose based on the metal oxide - carbon-dot hybrid structure was investig...
A simple, one-pot and ultrasensitive DNA sensor via Exo III-Assisted target recycling and 3D DNA walker cascade amplification.
Rapid, sensitive, and user-friendly nucleic acid detection is of growing importance in early clinical diagnosis. Here, we construct a simple, one-pot and ultrasensitiv...
Ultrasensitive electrochemical biosensor for attomolar level detection of let 7a based on toehold mediated strand displacement reaction circuits and molecular beacon mediated circular strand displacement polymerization.
In this study, an ultrasensitive electrochemical miRNA biosensor based on toehold mediated strand displacement reaction circuits (SDRCs) and molecular beacon mediated ...
Chiral Control of Carbon Dots via Surface Modification for Tuning the Enzymatic Activity of Glucose Oxidase.
Chiral carbon dots (CDs) integrated the advantages of achiral CDs and the unique chiral property, which expand the prospect of the biological applications of CDs. Howe...
Recombinant Antibody Engineering Enables Reversible Binding for Continuous Protein Biosensing.
Engineering antibodies to improve target specificity, reduce detection limits, or introduce novel functionality is an important research area for biosensor development...
Allosteric Regulation of DNA Circuits Enables Minimal and Rapid Biosensors of Small Molecules.
Detection of environmental pollutants is crucial to safeguard ecological and public health. Here, we report a modular biosensing approach for the detection of contamin...
Electrochemical detection of alkaline phosphatase activity through enzyme-catalyzed reaction using aminoferrocene as an electroactive probe.
As a nonspecific phosphomonoesterase, alkaline phosphatase (ALP) plays a pivotal role in tissue mineralization and osteogenesis which is an important biomarker for the...
Protease Biosensor by Conversion of a Homogeneous Assay into a Surface-Tethered Electrochemical Analysis Based on Streptavidin-Biotin Interactions.
This work proposed a new sensing strategy for protease detection by converting a homogeneous assay into a surface-tethered electrochemical analysis. Streptavidin (SA),...
Graphene nanocomposites for transdermal biosensing.
Transdermal biosensors for the real-time and continuous detection and monitoring of target molecules represent an intriguing pathway for enhancing health outcomes in a...
A fully screen-printed potentiometric chloride ion sensor employing a hydrogel-based touchpad for simple and non-invasive daily electrolyte analysis.
This is the first report demonstrating proof of concept for the passive, non-invasive extraction and in situ potentiometric detection of human sweat chloride ions (Cl-...
Intracellular arginine-dependent translation sensor reveals the dynamics of arginine starvation response and resistance in ASS1-negative cells.
BACKGROUND: Many cancers silence the metabolic enzyme argininosuccinate synthetase 1 (ASS1), the rate-limiting enzyme for arginine biosynthesis within the urea cycle. ...
Assembling Surface Linker Chemistry with Minimization of Non-Specific Adsorption on Biosensor Materials.
The operation of biosensors requires surfaces that are both highly specific towards the target analyte and that are minimally subject to fouling by species present in ...
Combination of Aptamer Amplifier and Antigen-Binding Fragment Probe as a Novel Strategy to Improve Detection Limit of Silicon Nanowire Field-Effect Transistor Immunosensors.
Detecting proteins at low concentrations in high-ionic-strength conditions by silicon nanowire field-effect transistors (SiNWFETs) is severely hindered due to the weak...
Optical bioelectronic nose of outstanding sensitivity and selectivity toward volatile organic compounds implemented with genetically engineered bacteriophage: Integrated study of multi-scale computational prediction and experimental validation.
Genetic engineering of a bacteriophage is a promising way to develop a highly functional biosensor. Almost countless configurational degree of freedom in the manipulat...
DNAzymes as key components of biosensing systems for the detection of biological targets.
DNAzymes are synthetic functional nucleic acids that have found widespread use in biosensing applications both for molecular recognition and signal generation. Two cla...
A Host-Guest Interaction-Based and Metal-Organic Gel-Based Biosensor with Aggregation-Induced Electrochemiluminescence Enhancement for Methyltransferase Assay.
Metal-organic gels (MOGs) are new soft materials with the characteristics of high colloidal stability, superb luminescence properties, and facile synthesis. Herein, we...
Entropy-driven amplification strategy-assisted lateral flow assay biosensor for ultrasensitive and convenient detection of nucleic acids.
Accurate, sensitive and rapid nucleic acid tests are important to implement timely treatment measures and control the spread of disease. Herein, we developed a novel p...
A distance-based capillary biosensor using wettability alteration.
Distance-based detection methods with a quantitative readout are of great significance to point-of-care testing (POCT), are low-cost and user-friendly, and can be inte...
Brain-machine and muscle-machine bio-sensing methods for gesture intent acquisition in upper-limb prosthesis control: a review.
This paper presents a review of a number of bio-sensing methods for gesture intent signal acquisition in control tasks for upper-limb prosthesis. The paper specificall...