Fluorescent Biosensors for Multiplexed Imaging of Phosphoinositide Dynamics.
Phosphoinositides constitute a critical family of lipids that regulate numerous cellular processes. Phosphatidylinositol 4,5-bisphosphate (PIP2) is arguably the most i...
Developing
Tryptamine is an alkaloid compound with demonstrated bioactivities and is also a precursor molecule to many important hormones and neurotransmitters. The high efficien...
The small fiber neuropathy NaV1.7 I228M mutation: impaired neurite integrity via bioenergetic and mitotoxic mechanisms, and protection by dexpramipexole.
Gain-of-function variants in voltage-gated sodium channel NaV1.7 that increase firing frequency and spontaneous firing of dorsal root ganglion (DRG) neurons have recen...
Nanoparticle Reservoirs for Paper-Only Immunosensors.
Biosensors made entirely of paper are becoming increasingly popular due to their low cost, facile fabrication, and lightweight portability for in-field measurements. H...
Lattice-Like DNA Tetrahedron Nanostructure as Scaffold to Locate GOx and HRP Enzymes for Highly Efficient Enzyme Cascade Reaction.
In this work, the array arrangement of cascade enzymes was implemented by alternately and equidistantly anchoring two model enzymes glucose oxidase (GOx) and horseradi...
The effect of anode hydrodynamics on the sensitivity of microbial fuel cell based biosensors and the biological mechanism.
Fluid dynamics in the anodic chamber of a microbial fuel cell (MFC) is a key factor affecting the distribution of substrates and the efficiency of mass transport. Howe...
Nanomagnet-Silica Nanoparticles Decorated with Au@Pd for Enhanced Peroxidase-Like Activity and Colorimetric Glucose Sensing.
Nanomagnet-silica shell (Fe3O4@SiO2) decorated with Au@Pd nanoparticles (NPs) were synthesized successfully. The characterization of Fe3O4@SiO2-NH2-Au@PdNPs was achiev...
Target-Driven Cascade-Amplified Release of Loads from DNA-Gated Metal-Organic Frameworks for Electrochemical Detection of Cancer Biomarker.
In this paper, a label-free and stimuli-responsive electrochemical biosensing platform was fabricated based on target-driven load release from DNA-gated metal-organic ...
Dual platform based sandwich assay surface-enhanced Raman scattering DNA biosensor for the sensitive detection of food adulteration.
Surface enhanced Raman scattering (SERS) DNA biosensing is an ultrasensitive, selective, and rapid detection technique with the ability to produce molecule-specific di...
Intramolecular photoinitiator induced atom transfer radical polymerization for electrochemical DNA detection.
A novel electrochemical biosensor was reported for the first time to achieve highly sensitive DNA detection based on photoinduced atom transfer radical polymerization ...
Rapid strand replacement primer thermostat visual sensor based on Bst DNA polymerase and pyrophosphatase for detecting Vibrio parahaemolyticus.
Vibrio parahaemolyticus is a major hidden danger of food safety. To develop a rapid, sensitive and on-site detecting method of Vibrio parahaemolyticus (V. parahaemolyt...
Identification, Characterization, and Application of a Highly Sensitive Lactam Biosensor from
Caprolactam is an important polymer precursor to nylon traditionally derived from petroleum and produced on a scale of 5 million tons per year. Current biological path...
Nanographite-based fluorescent biosensor for detecting microRNA using duplex-specific nuclease-assisted recycling.
The development of a nanographite (NG)-based fluorescent biosensor for detecting microRNA (miRNA) is reported. Duplex-specific nuclease (DSN)-assisted signal amplifica...
Recent advances in nucleic acid-based methods for detection of helminth infections and the perspective of biosensors for future development.
Pathogenic helminth infections are responsible for severe health problems and economic losses worldwide. Timely and accurate diagnosis of helminth infections is critic...
Controlled fabrication of gold nanobipyramids/polypyrrole for shell-isolated nanoparticle-enhanced Raman spectroscopy to detect γ-aminobutyric acid.
Shell-isolated nanoparticle-enhanced Raman Spectroscopy (SHINERS) has been a non-destructive, highly sensitive, specific and powerful sensing method. Detection of γ-am...
One-step electrodeposition of poly(m-aminobenzoic acid) membrane decorated with peptide for antifouling biosensing of Immunoglobulin E.
m-Aminobenzoic acid (ABA) is one popular derivative of highly conductive monomer of aniline, which contains a carboxyl (COOH) group in its skeleton that is beneficial ...
Construction of manganese oxide nanowire-like cluster arrays on a DNA template: Application to detection of hydrogen peroxide.
Improved electron transfer properties and catalytic activity of manganese oxide (MnOx) was demonstrated following its electrochemical deposition on a deoxyribonucleic ...
Thermo-sensitive surface molecularly imprinted magnetic microspheres based on bio-macromolecules and their specific recognition of bovine serum albumin.
Bovine serum albumin imprinted magnetic microspheres, with functional monomers of modified chitosan, N-isopropylacrylamide and sulfobetaine methacrylate, were successf...
Electrochemical determination of uric acid in urine and serum with uricase/carbon nanotube /carboxymethylcellulose electrode.
The detection of uric acid in blood and urine is clinically important in terms of suitable diagnosis and self-healthcare. An amperometric thin film biosensor composed ...
Microbial fuel cell-based biosensor for online monitoring wastewater quality: A critical review.
Recently, the application of the microbial fuel cell (MFC)-based biosensor for rapid and real-time monitoring wastewater quality is very innovative due to its simple c...