Extracellular vesicles (EVs) have emerged as promising biomarkers for the diagnosis and monitoring of various diseases; however, their clinical application is limited ...
The engineered formation of ternary complexes, in which two proteins are bridged by small molecules such as PROTACs or molecular glues, is a prerequisite for the targe...
Early and accessible diagnosis of tuberculosis (TB) remains a global health challenge, particularly in low- and middle-income countries. Early Secreted Antigenic Targe...
Locked nucleic acids (LNAs) are chemically modified oligonucleotides widely used in gene silencing and precision oncology, yet their clinical translation is limited by...
Radiation-induced skin injury (RISI) affects over 95% of radiotherapy patients. Current clinical management remains confined to passive supportive care, lacking mechan...
An electrochemical immunosensor based on multiwalled carbon nanotube/zinc oxide nanoparticle (MWCNTs/ZnONPs) composites was fabricated for the sensitive and selective ...
Urinary tract infections (UTI) are among the most prevalent infectious diseases, demanding rapid diagnosis to provide timely therapeutic interventions. Urinary molecul...
Biocompatibility of a biosensor can be achieved by grafting polymer brushes onto a solid surface. These brushes must be able to attract specific analytes or repel unwa...
We hypothesized that Restless Legs Syndrome (RLS) and the restlessness of opioid withdrawal share common neurobiological mechanisms based on the efficacy of μ-opioid r...
To meet the urgent demand for monitoring tetracycline residues in milk-a critical food for vulnerable groups a novel fiber-optic Localized Surface Plasmon Resonance (L...
Miniaturized technologies, including small, portable, or wearable devices such as biosensors, smartwatches, and implantable devices, are transforming health and wellne...
Functional regeneration of bone and cartilage remains an urgent clinical challenge in orthopedics, as its repair process involves the synergistic participation of mult...
Infrared spectroscopy provides label-free access to protein structure information with high sensitivity. Challenges in infrared spectroscopy include artifacts arising ...
Phenylketonuria (PKU) is a rare metabolic disorder causing elevated phenylalanine (PHE) levels requiring lifelong dietary or pharmacological management and regular mon...
Trigeminal neuralgia (TN) is the most common neuropathic disorder; however, its pathogenesis remains unclear. A prevailing theory suggests that nitric oxide (NO) may i...
Molecularly imprinted polymer (MIP) interfaces offer antibody-level selectivity without bioreceptor instability, yet their integration into transistor-based sensors re...
Salivary diagnostics for oral squamous cell carcinoma (OSCC) and oral potentially malignant disorders (OPMD) have advanced significantly, yet clinical translation rema...
Genetically encoded biosensors provide powerful tools for coupling desired phenotypes to detectable outputs and have been extensively developed to detect a wide range ...
Malaria remains to be one of the deadliest infectious illnesses and is especially common in underdeveloped and developing countries. Recent advances (2022–2025) in bio...
Continuous, in vivo drug and biomarker measurements could transform healthcare, enabling both the high-precision personalization of drug dosing and the real-time monit...