A Combinatorial Electrochemical Biosensor for Sweat Biomarker Benchmarking.
Misclassification of an acute disease condition as chronic and vice versa by electrochemical sweat biomarker sensors can cause significant psychological, emotional, an...
Voltage-dependent activation of Rac1 by Na
Ion channels can regulate the plasma membrane potential (Vm ) and cell migration as a result of altered ion flux. However, the mechanism by which Vm regulates motility...
A fluorescent lateral flow biosensor for the quantitative detection of Vaspin using upconverting nanoparticles.
Vaspin is a protein present in human serum that can cause type-2 diabetes, obesity, and other cardiovascular diseases. We report fluorescent upconverting nanoparticles...
A highly sensitive colorimetric aptasensor for the detection of the vascular endothelial growth factor in human serum.
Early detection of cancer is of great significance for disease prevention and diagnosis. However, the levels of most cancer markers are quite low in the early stages o...
Acetylcholinesterase biosensors based on ionic liquid functionalized carbon nanotubes and horseradish peroxidase for monocrotophos determination.
Long-term and excessive use of monocrotophos (MPs) pesticide leads to an accumulation of MPs residues in agricultural products. Electrochemical biosensor technology wa...
Self-reduction bimetallic nanoparticles on ultrathin MXene nanosheets as functional platform for pesticide sensing.
Two-dimensional (2D) transition metal carbides and nitrides, named MXene, appear promising application prospects in sensor filed. Metal nanoparticles, especially bimet...
A ratiometric electrochemical DNA biosensor for detection of exosomal MicroRNA.
The detection of exosomal microRNAs (miRNAs) derived from cancer cells with sensitive and selective methods has stimulated increasing interest due to its potential uti...
Optimization of 3-aminopropyltriethoxysilane functionalization on silicon nitride surface for biomolecule immobilization.
The 3-aminopropyltriethoxysilane (APTES) is a common method for biomolecule immobilization on silicon and silicon derivatives such as silicon nitride (Si3N4). However,...
A DNA electrochemical biosensor based on triplex DNA-templated Ag/Pt nanoclusters for the detection of single-nucleotide variant.
A label-free electrochemical biosensor based on the triplex DNA-templated Ag/Pt bimetallic nanoclusters (triplex-Ag/PtNCs) and locked nucleic acid (LNA) modified X-sha...
Autocatalytic DNA circuit for Hg
Utilizing G-quadruplex as the signal report probe, an ultrasensitive and label-free autocatalytic DNA circuit for Hg2+ detection on the basis of exonuclease III (Exo I...
Ultrasensitive fluorescent detection of HTLV-II DNA based on magnetic nanoparticles and atom transfer radical polymerization signal amplification.
Human T-lymphotropic virus type II (HTLV-II) is a crucial retrovirus that is closely associated with a variety of human diseases. Herein, an ultrasensitive fluorescent...
Latest developments in the detection and separation of bovine serum albumin using molecularly imprinted polymers.
Recently, enormous attention has been focused on the development of protein-molecularly imprinted polymers (MIPs). In this sense, bovine serum albumin (BSA) is well re...
Sodium hexametaphosphate modulated fluorescence responsive biosensor based on self-assembly / disassembly mode of reduced-graphene quantum dots / chitosan system for alkaline phosphatase.
Herein, a sodium hexametaphosphate ((NaPO3)6) modulated fluorescence responsive probe based on the integration of reduced graphene quantum dots (rGQDs) and chitosan (C...
A "signal-on" chemiluminescence biosensor for thrombin detection based on DNA functionalized magnetic sodium alginate hydrogel and metalloporphyrinic metal-organic framework nanosheets.
A "signal-on" chemiluminescence biosensor was established for detecting thrombin. The thrombin aptamer1-functionalized magnetic sodium alginate (Malg-Apt1) hydrogel wa...
Reflectance aptasensor based on metal salphen label for rapid and facile determination of insulin.
An optical aptasensor-based sensing platform for rapid insulin detection was fabricated. Aminated porous silica microparticles (PSiMPs) were synthesized via a facile m...
Development of the simultaneous colorimetric enzymatic detection of sucrose, fructose and glucose using a microfluidic paper-based analytical device.
Herein, we propose the first fabrication of a microfluidic paper-based analytical device (μPAD) as a simple, rapid and selective method for the simultaneous detection ...
Biocompatible AIE material from natural resources: Chitosan and its multifunctional applications.
New sources of AIE materials with good water solubility, biocompatibility, degradability, and mass production are urgently needed. Here, we found that chitosan, a very...
Construction of sponge-like graphitic carbon nitride and silver oxide nanocomposite probe for highly sensitive and selective turn-off fluorometric detection of hydrogen peroxide.
In the present work, spongy graphitic carbon nitride (GCN) and silver oxide nanocomposites were prepared through a facile hydrothermal method at 160 °C for 4 h using G...
Rapid and sensitive detection of interleukin-6 in serum via time-resolved lateral flow immunoassay.
Interleukin 6 (IL-6) is an interleukin that acts as both a proinflammatory and anti-inflammatory cytokine. It can be used as a potential diagnostic biomarker for sepsi...
Synthetic Biology Enables Programmable Cell-Based Biosensors.
Cell-based biosensors offer cheap, portable and simple methods of detecting molecules of interest but have yet to be truly adopted commercially. Issues with their perf...